Which medication is commonly prescribed to reverse the effects of opioid overdoses?

Naloxone, commonly known by the brand name Narcan, is specifically designed to reverse the effects of opioid overdoses. It works by competitively binding to the same receptors in the brain that opioids bind to, thereby reversing the respiratory depression, sedation, and hypotension that can occur during an overdose. This rapid action allows for quick restoration of normal breathing in patients experiencing an opioid overdose, making it a critical medication in emergency situations.

Other medications listed serve different purposes; for instance, Ativan (lorazepam) is a benzodiazepine used mainly for anxiety, seizures, and sedation, but does not treat opioid overdose. Flumazenil is a benzodiazepine antagonist but should not be used for opioid overdose due to the risk of seizures and complications. Glycopyrrolate is an anticholinergic used primarily to reduce salivation and secretions, particularly during anesthesia, and has no role in reversing opioid effects. Therefore, naloxone is the go-to choice for effectively addressing opioid overdoses in clinical practice.